lab sculpture created by Steve Lohman

 

Postdoctoral ScholarsGraduate Students
Mark Schnitzer
Principal Investigator
CONTACT CURRICULUM VITAE

Mark Schnitzer is Professor of Biology and Applied Physics and is an Investigator of the Howard Hughes Medical Institute. His research concerns the innovation of novel optical imaging technologies and their use in the pursuit of understanding neural circuits. The Schnitzer lab has invented two forms of fiber-optic imaging, one- and two-photon fluorescence microendoscopy, which enable minimally invasive imaging of cells in deep brain tissues. The lab is further developing microendoscopy technology, studying how experience or environment alters neuronal properties, and exploring two different clinical applications. The group has also developed two complementary approaches to imaging neuronal and astrocytic dynamics in awake behaving animals. Much research focuses on cerebellum-dependent forms of motor learning. By combining imaging, electrophysiological, behavioral, and computational approaches, the lab seeks to understand cerebellar dynamics underlying learning, memory, and forgetting. Further work in the lab concerns neural circuitry in other mammalian brain areas such as hippocampus and neocortex, as well as the neural circuitry of Drosophila.

Annette Lewis
Scientific Project Manager
CONTACT  

After completing postdoctoral research in neuroscience at Stanford and Genentech, Inc., I worked as a scientist and scientific manager at Entelos, Inc., working closely with both biologists and engineers to build computer based models of disease, including asthma and other inflammatory diseases. I have returned to Stanford to apply principles of scientific management to the work in the Schnitzer lab, where innovation of new brain imaging modalities involves detailed planning and coordination between several personnel with distinct areas of expertise. I also help coordinate our relationships with scientific corporations seeking to translate our inventions into the marketplace.

Cheng Huang
Research Scientist
CONTACT  

As a graduate student with Dr. Yi Zhong at Tsinghua University, I studied the molecular and cellular basis of olfactory long-term memory in Drosophila. In the Schnitzer lab, I am using a variety of approaches to dissect the neural circuitry underlying adaptive behavior of Drosophila. I am also involved in the effort to create massively parallel, high-throughput brain imaging technologies.

Tony Hyun Kim
Research Specialist III, HHMI
CONTACT  

I am motivated by the possibility of uncovering hitherto unknown computational structures and concepts by careful experimental work in neuroscience. During my Ph.D. in Electrical Engineering, I developed novel optical technologies and applied them to the study of distributed brain circuits in behaving animal subjects. My current research combines multiple optical techniques, detailed studies of animal behavior, and quantitative modeling of circuits, with the aim of rigorously characterizing computational processes in the live brain.

Jane Li
Life Science Research Assistant
CONTACT  

I support the laboratory through a variety of research activities involving histology, circuit tracing, genotyping, husbandry, and surgery.

Thomas Rogerson
Research Scientist
CONTACT  

Memories are often constructed from associations between diverse pieces of information that have no intrinsic connection. By studying how disparate pieces of information are stored in relation to each other, I hope to shed light on the mechanisms by which memories are linked in the mammalian brain. This will facilitate our understanding of how higher order knowledge is extracted from multiple memories.

Yanping Zhang
Research Technician III, HHMI
CONTACT  

I have more than ten years experience in molecular and cell biology with both laboratory and clinical experience, designing and constructing cloning and expression vectors for gene expression and regulation, performing mutagenesis, protein preparation, and DNA/RNA analysis. In the Schnitzer lab, I continue to work on molecular cloning and systematic viral production.

Postdoctoral Scholars
Behnam Abaie
Postdoctoral Scholar
CONTACT  

Optical imaging plays an important role in how neuroscientists study the structure and function of the live nervous system. My postdoctoral research in the Schnitzer lab focuses on the development of new optical imaging modalities for tracking complex patterns of neural activity in awake behaving animals.

Jordi Fernandez Albert
Postdoctoral Scholar
CONTACT  

Learning and memory, neuronal plasticity, and many brain diseases involve profound changes in transcriptional regulation. As a joint postdoc with the labs of Mark Schnitzer and William Greenleaf, I am investigating how transcriptional regulation relates to neural activity in healthy and diseased brains.

Radoslaw Chrapkiewicz
Postdoctoral Scholar
CONTACT  

Large-scale optical imaging of neural ensemble dynamics is nowadays the most promising way to unveil unexplored features of brain activity. During my Ph.D. studies in quantum optics, I developed new techniques of storing and imaging the spatial structure of single photons. My current research will focus on providing new optical tools to efficiently extract signals from genetically encoded neural activity indicators under hitherto technically unattainable conditions.

Sadegh Ebrahimi
Postdoctoral Scholar
CONTACT  

As a computational and systems neuroscientist, I am interested in understanding how can cognition emerge from networks of relatively simple computational units? My Ph.D in electrical engineering and experience analyzing large-scale neural activity datasets are helping me to address this question with a variety of theoretical, experimental, and computational techniques. I am especially interested in how the brain uses internal models of the outside world to predict future outcomes, and in employing similar mechanisms to create artificial intelligent systems with capabilities resembling those of the mammalian brain.

Simon Haziza
Postdoctoral Scholar
CONTACT  

How the brain's many different types of neurons synchronize their electrical dynamics to generate extended brain oscillations is a longstanding and important question. With my joint background in neuroscience and physics, I am developing and applying new ways to probe the brain's voltage rhythms by using genetically encoded fluorescent voltage indicators.

Oscar Hernandez
Postdoctoral Scholar
CONTACT  

The perception of objects may be encoded by the coordinated neural activity of only thousands of cells. Thanks to recent technological developments, we can generally access and manipulate such information optically. My research focuses on the development of innovative optical systems that may elucidate precise causal links between neural activity and the neural representation of objects.

Xiqian Jiang
Postdoctoral Scholar
CONTACT  

During my Ph.D. research at Baylor College of Medicine, I developed several reversible, ratiometric fluorescent probes for glutathione. Now I am interested in applying novel techniques, especially imaging and omics-based assays, to study the molecular mechanisms underlying learning and memory and diseases thereof.

Jizhou Li
Postdoctoral Scholar
CONTACT  

From my Ph.D. work, I am an expert in computational image processing. I am now working with the Schnitzer lab to extend brain-imaging capabilities through further development of computational algorithms for image reconstruction.

Junjie Luo
Postdoctoral Scholar
CONTACT  

I am using genetic and optical tools developed by the Schnitzer lab to dissect and characterize the dynamics of the olfactory learning and memory circuit in adult Drosophila.

Adam Shai
Postdoctoral Scholar
CONTACT  

Sensory processing and the brain's creation of perceptions form the bedrock of our experience, and yet their neural mechanisms remain enigmatic. By studying the dynamics of cortical processing during perceptual tasks, I hope to uncover the computational principles by which representations are formed in the cortex, and the biological mechanisms that carry out such computations.

Albert Tsao
Postdoctoral Scholar
CONTACT  

I performed my Ph.D. research at the Kavli Institute in Norway with Edvard and May-Britt Moser. My present research examines how ideas and insights arise in the brain by using large-scale optical recordings to track the dynamics of large populations of neurons in behaving animals.

Michael White
Postdoctoral Scholar
CONTACT  

Existing models propose that perception requires neocortex, but scientists do not yet understand cortical function well. I am using technology developed in the Schnitzer Lab to image neocortex of awake, behaving mice from large-scale ensembles to dendritic spines to gain new insight into how this prominent brain structure functions.

Paul Yuan
Postdoctoral Scholar
CONTACT  

It has been proposed that the brain areas responsible for perceptual processing are the same as those involved in memorization. Utilizing innovative optical tools, I am interested in identifying and manipulating the neural activity ensembles associated with specific memories. I hope to learn the underlying principles at the cellular level for memory encoding and decoding through this work.

Graduate Students
Amy Christensen
Graduate Student
CONTACT  

I am interested in combining large scale optical recordings, rodent behavioral assays, and computational models, to further understanding of cortical sensory processing. My work is informed by my formal training in Electrical Engineering and laboratory experiences in Neuroscience.

Fatih Dinc
Graduate Student
CONTACT  

My interest lies at the intersection between neuroscience and computer science. Using machine learning methods and brain imaging data from mice, I aim to tap into the internal neural circuitry of the brain and understand the neural ensemble dynamics underlying memory formation and recollection in the short- and long-term. I received my undergraduate training as an electrical engineering in Turkey and my masters in theoretical physics in Canada. As an applied physics Ph.D. student at Stanford, I use a wide range of methods to tackle the interdisciplinary research questions we ask in the Schnitzer lab.

Omer Hazon
Graduate Student
CONTACT  

I am interested in understanding the emergent properties of large neural ensembles and the principles behind neural coding using imaging datasets and connectionist models.

Yuxi Ke
Graduate Student
CONTACT  

I am a bioengineering Ph.D. student and am interested in uncovering the relationships between neural ensemble activity patterns in behaving animals and the macromolecular changes that support learning and memory.

Jessica Maxey
Graduate Student
CONTACT  

I am interested in developing methods to analyze neural data collected using functional imaging as well as developing computational models based on observed neural patterns. My work is supported by my undergraduate background in electrical engineering.

Tugce Tasci
Graduate Student
CONTACT  

My interest is in computational neuroscience, particularly analysis of neural data obtained from one and two photon imaging, which is becoming a critical bottleneck as the complexity of data acquired from brain imaging studies increases. I specialized in signal/image processing during my undergraduate studies in electrical engineering.

Fori Wang
Graduate Student
CONTACT

I am interested in using optical tools to study circuit dynamics in awake behaving animals. My research draws on my background in neuroscience and bioengineering.

Seung Je Woo
Graduate Student
CONTACT

I am interested in developing technologies that will lead to a better understanding of neural circuits in Drosophila. Specifically, I am creating machine-vision capable robots for manipulating fruit flies and compact microscopes for parallel, high-throughput brain imaging.